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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
30.3
Human Site:
S356
Identified Species:
47.62
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
S356
V
L
I
D
K
D
Q
S
P
K
W
K
P
A
D
Chimpanzee
Pan troglodytes
XP_515988
440
48807
S410
V
L
I
D
K
D
Q
S
P
K
W
K
P
A
D
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
S414
V
L
I
D
K
D
Q
S
P
K
W
K
P
A
D
Dog
Lupus familis
XP_848689
359
39946
P330
L
I
D
K
D
Q
S
P
K
W
K
P
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
T355
V
L
I
D
K
D
Q
T
P
K
W
K
P
A
N
Rat
Rattus norvegicus
Q5XIE6
385
43006
T355
V
L
I
D
K
D
Q
T
P
K
W
K
P
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
S355
V
L
I
D
K
D
Q
S
P
R
W
K
P
A
A
Frog
Xenopus laevis
A2VDC2
385
42348
K355
V
L
I
D
K
D
Q
K
A
K
W
K
P
E
S
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
S352
V
L
I
D
K
D
Q
S
P
K
W
K
P
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
K354
L
L
I
D
K
D
Q
K
P
Q
W
Q
P
T
K
Honey Bee
Apis mellifera
XP_396249
396
44074
K356
V
L
I
D
K
D
R
K
P
K
W
N
P
K
N
Nematode Worm
Caenorhab. elegans
P34559
288
31153
R259
E
G
L
H
F
E
R
R
L
F
H
A
T
F
A
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
T349
V
L
I
E
K
D
H
T
P
K
W
S
P
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
D346
D
V
T
D
S
M
V
D
Q
Y
F
E
R
V
E
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
E445
Q
E
I
A
A
Y
I
E
K
R
T
N
D
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
0
N.A.
86.6
93.3
N.A.
N.A.
86.6
73.3
86.6
N.A.
60
66.6
0
66.6
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
93.3
73.3
93.3
N.A.
80
80
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
7
0
0
0
7
0
0
7
7
47
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
74
7
74
0
7
0
0
0
0
7
14
27
% D
% Glu:
7
7
0
7
0
7
0
7
0
0
0
7
0
7
7
% E
% Phe:
0
0
0
0
7
0
0
0
0
7
7
0
0
7
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
0
7
80
0
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
74
0
0
20
14
60
7
54
0
7
7
% K
% Leu:
14
74
7
0
0
0
0
0
7
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
7
67
0
0
7
74
0
0
% P
% Gln:
7
0
0
0
0
7
60
0
7
7
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
14
7
0
14
0
0
7
0
0
% R
% Ser:
0
0
0
0
7
0
7
34
0
0
0
7
0
7
7
% S
% Thr:
0
0
7
0
0
0
0
20
0
0
7
0
7
7
20
% T
% Val:
67
7
0
0
0
0
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
74
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _